乳腺浸润性导管癌 免疫组化ER(3+)，PR(3+)，Her-2(-), P63、CK5/6显示导管肌上皮细胞缺失，Ki67标记指数9%

Question

免疫组化ER(3+)，PR(3+)，Her-2(-), P63、CK5/6显示导管肌上皮细胞缺失，Ki67标记指数9%。乳腺活检标本）灰白肿物一个，体积：2.5cmx2cmx1cm,部分包膜，切面灰白灰黄。
光镜所见：乳腺异型细胞呈腺管状排列，部分呈筛孔状，细胞核为圆形，排列拥挤。
病理诊断：乳腺浸润性导管癌（WHO I级，5分）

以上情况严重吗？以后最好如何治疗？

Answer 1

ER是雌激素受体，PR是孕激素受体，两者与内分泌治疗密切相关。Her-2癌基因的过度表达是乳腺癌患者预后差的指证。ER、PR阳性，Her-2阴性的患者进行三苯氧胺治疗可取得良好的效果。而三者同时阳性的患者，采用三苯氧胺治疗并无意义，甚至更差。相反Her-2的高表达，以及KI67的增殖指数越高，表明肿瘤的恶性程度越高，预后越差。从上面指标的表达来看应该比较乐观，应到肿瘤科积极治疗，当然，最终影响疗效的原因是多方面的，如：个人体质、对药物敏感度、肿瘤的范围等等，最重要的还是心态，这一点尤为重要。

Answer 2

没有介绍淋巴结转移情况，根据目前资料看情况不算严重。ER,PR都是强阳性，说明对内分泌治疗比较敏感，效果会比较好。病理级别也较低，Her-2还是阴性。说明恶性程度低。应积极配合治疗。完善化疗和内分泌治疗，会有良好的预后。

Answer 3

This qiu dong, besides big play animal grain, the military uniform, besides restoring ancient

ways, bowknot sheet is tasted is best choice. Amy fashionable you must give the bowknot wore

the! Coat, dress,MLB Jerseys, sweaters, even ma3 jia3 can blend in bowknot elements, see its joker and

fashion! Different bowknot on body, can have different sense!
dress

Double platoon to buckle woollen vest skirt waist, bowknot adornment. Warm degree good, tie-

in a render unlined upper garment dress,Coach Shoulder Bags, love ~ this year qiu dong necessary sheet is tasted!

Lady delicate all hand pearl bowknot of sleeve dress, cultivate one's morality show thin,

comfortable breathe freely,P90X Workout, apeak feeling slightly massiness, accord with autumn. Has good

elasticity, manifests body model. All hand nail bead,Mens Custom Timberland Boots, pearl also is to use colorfast high-

quality goods!
Lady delicate all hand pearl bowknot of sleeve dress, cultivate one's morality show thin,

comfortable breathe freely, apeak feeling slightly massiness, accord with autumn. Has good

elasticity, manifests body model. All hand nail bead, pearl also is to use colorfast high-

quality goods!
Lady bowknot wool NeDaYi, princess style lantern sleeve and collar place bowknot appears very

pretty lady. And A word skirt again for the whole yiyibushe added many temperament, whether

date or shopping, they will be the center of attention!
Expensive gas seven minutes of sleeve bowknot maomao coat, silk fabrics bowknot don't in

collar, maomao elegant, 7 minutes of sleeve flared design foil a ribbon bowknot of high

temperament, very the queen's one!
Brief paragraph long-sleeved pearl bowknot sweater cardigan coat, be full of clothes on small

bowknot is absolutely butterflies control favourite, stars dotted half pearl fill the blank,

sweet and grace hold concurrently!
BianFuShan big bowknot loose sweaters, beauties the temperament of a paragraph, super yards

loose, stripe round brought bowknot long-sleeved sweater, any shape MM can wear!
OL perfect intellectual butterfly ma3 jia3,p90x, suit version to design increases intellectual

beauty, especially suitable for walk handsome route of MM, optional simple bowknot added with

a woman flavour!

Topics related articles：

Cheap Tiffany Rings Beautiful coat coat recommende

Discount Gucci Handbags Qiu dong the bowknot non-b

Fendi Handbags You buy IT by qiu dong BAG

Answer 4

乳腺癌的主要症状表现为：乳腺肿块、乳腺疼痛、乳头溢液、乳头改变、皮肤改变、腋窝淋巴结肿大。
乳腺癌特效验方“孔氏乳癌散瘀汤”能够真正达到减少痛苦、减轻症状、提高生存质量、有效抑制复发和转移、延长生命的目的。使乳腺癌治疗走向科学化、规范化、专业化，实现了肺癌治疗的整体、针对性和有效性。孔教授根据“孔氏乳癌散瘀汤”药理药性及多年乳腺癌治疗经验，首创清肿块抑癌疗法，是乳腺癌治疗史上的重大突破，是迄今为止乳腺癌医学领域最新的科学治疗方法之一，为乳腺癌医学领域提供了一整套切实可行、行之有效的治疗方案，为提高中医在肿瘤治疗领域的地位和声誉作出重大贡献。